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Mathematical Modelling for Disease Control

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By Mercy Kelani

They reduce the effect of outbreaks by giving info needed for right decisions.

Through the simulation of disease progression and the assessment of intervention options, mathematical modelling is a vital tool in the prediction and management of infectious disease outbreaks. These mathematical models reduce the effect of outbreaks like the Mpox virus by giving Public Health officials the information they need to make educated decisions. Models were essential during the 2014 Ebola outbreak, when experts pinpointed important pathways of transmission and suggested measures like isolation and quarantine for hospitals, which greatly slowed the disease’s spread. Differential equations were used to highlight the need of safe burial practices in containing the pandemic.

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By January 2015, there have been more than a million cases in Liberia. International measures, such as the deployment of healthcare personnel and resources, were spurred by this catastrophic forecast. The implementation of proper burial practices and hospital isolation, as recommended by models, proved to be crucial in controlling the outbreak within around a year. The ultimate case count was approximately 28,000, which was far lower than the worst-case scenarios. The use of these models in resource allocation—such as the placement of isolation units and personal protective equipment—proved crucial in keeping the virus contained.

Controlling diseases in Nig. has been influenced by mathematical models.

Infectious disease control has historically benefited from the development of mathematical models, which are still useful today thanks to the work of pioneers like Sir Ronald Ross. His model from 1911 established key ideas including the basic reproduction number (R0), which calculates the potential for disease propagation. Current models range in complexity from agent-based models that concentrate on individual and community behaviours to deterministic models that provide a comprehensive perspective of Epidemic trends, all of which were heavily utilised during the COVID-19 pandemic. Controlling diseases like Malaria and COVID-19 in Nigeria has been greatly influenced by mathematical models.

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During the COVID-19 epidemic, Nigeria’s lockdown policies were shaped in large part by models created by the Nigeria Centre for Disease Control (NCDC). Early in the epidemic, simulations predicted that Nigeria might experience a sharp increase in COVID-19 cases that would overwhelm the country’s healthcare system if there was no national lockdown. In March 2020, the authorities enforced a severe lockdown based on these projections. Data from the models, which indicated that extended lockdowns may have negative social and economic effects, was also helpful in developing the gradual reopening plan.

Models with insufficient or erroneous data may not be trustworthy.

In order to prevent the spread of COVID-19 and save lives, models that predicted the virus’s course made sure Nigeria adopted targeted interventions including regional lockdowns and quarantine measures. High-quality data is one of the main obstacles in mathematical modelling. Models with insufficient or erroneous data may not be trustworthy. Enhancements to the systems used to collect health data are crucial to solving issue. Digital health platforms, which collect data from healthcare institutions in real-time and provide more precise and timely inputs for models, are one technical option.

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For instance, quick reporting and data sharing on disease outbreaks among African nations is made possible via the Surveillance Outbreak Response Management and Analysis System (SORMAS) of the Africa CDC. Increasing the usage of these platforms could guarantee that models have access to current, reliable data. It is imperative that policymakers embrace and act upon model outputs. It is imperative that they guarantee the use of mathematical models into both national and local health decision-making procedures. In order to improve and advance mathematical models, researchers are essential. Through the development of more realistic models that account for the intricacy of disease transmission, scientists may provide health officials practical insights.

Related Article: FG Launches New Policies to Tackle Diseases

The effectiveness of model-driven tactics depends on public participation. Public trust and compliance can rise with awareness efforts that tell people about how health policy are informed by mathematical models. In order to obtain useful data for more accurate modelling, the public must also be involved in data collection activities. Examples of these include self-reporting symptoms through mobile apps or taking part in community health surveys. Nigeria and other nations may fully utilise the potential of mathematical modelling to enhance public health outcomes by promoting deeper relationships among various stakeholders and making use of both domestic and foreign resources.

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